What Every Woman Needs to Know About Blood Clots

by , April 8, 2012 — 12 Comments
What Every Woman Should Know About Blood Clots

Kate, a 28-year-old development professional, was uploading snapshots of Mai Tais and Maui sunsets from her Hawaiian honeymoon when she noticed a pain in her calf that felt like a pulled muscle. At night, the pain was so intense that it woke her up, so she went to an orthopedic surgeon who ordered a scan.

The test didn’t show any issues, so she forgot about it, until seven months later, when the newlyweds hopped a plane to San Francisco. On the return layover, Kate exited the plane, felt dizzy, and passed out in the terminal. The alarmed couple rented a car and drove back home to North Carolina, where she saw a doctor again. He chalked it up to dehydration.

Then Kate started experiencing something new on her daily five-mile walks: “I was kind of short of breath. Since it was my first summer in North Carolina, I thought it was allergies or maybe that I was out of shape—so I would go extra hard on the elliptical machine.” She didn’t share her symptom with anyone and soon became preoccupied with packing for a family trip to Alaska and Seattle.

As she waved hello to Starbucks’ stomping grounds from the Space Needle, Kate was completely unaware of the killer in her right calf. A massive blood clot, or deep vein thrombosis (DVT), had formed in her lower right leg and was releasing smaller clots that were traveling to her lungs.

These blood clots in the lungs, called pulmonary emboli (PE), “can be life-threatening and in 10-15% of cases, cause sudden death,” says Dr. Jack Ansell, MD, hematologist and chairman of the Department of Medicine at Lenox Hill Hospital in New York and member of the National Blood Clot Alliance’s Medical Advisory Board. “The first sign of a PE can be death.”

As the trip progressed, Kate had an increasingly difficult time catching her breath. She couldn’t shake the feeling “that something was wrong,” but boarded the plane with a pack of M&M’s and told herself everything would be OK.

Mid-flight, she got up to use the bathroom and collapsed in the middle of the aisle. A group of firemen on board gave her oxygen, and upon landing, an ambulance whisked her to an Atlanta ER where she was diagnosed with dehydration and vasovagal reaction (a fainting episode). She immediately flew back to North Carolina and scheduled an urgent doctor visit. As she prepped for her appointment, she collapsed again after climbing the stairs.

“I called 911, and the [paramedics] didn’t think anything major had happened,” she recalls. “They said, ‘wait until your husband gets home and he can take you to the doctor.’”

Luckily for Kate, a mother’s instinct was on her side. Her mom (a nurse) suggested that a blood clot might explain Kate’s mystery malady. Her doctor ordered a V-Q scan (a specialized lung test), and found multiple PEs in both lungs. Kate—a healthy young woman whose only risk factors were a series of flights longer than five hours and the daily birth control pill she popped—was in danger of having a heart attack.

Although Dr. Ansell states that the actual frequency of DVTs is low in young people, he emphasizes that it’s essential to know about the risk. “This should not be called an epidemic, but about 100,000 people die each year as a result and there are upwards of 500,000-600,000 cases per year.”

Take a lesson from Kate’s story, and read on for what you need to know.

 

Acquaint Yourself With the Symptoms

Kate was lucky to escape with her life, but knowing the warning signs could have gotten her more immediate medical attention. Shortness of breath, chest pain (particularly with deep breathing), coughing up blood, persistent leg pain, or redness, swelling, or warmth in your lower legs (usually one-sided) can all be indications of a blood clot in the legs or lungs, and should never be ignored.

And, give yourself a break already. “Women tend to beat themselves up about losing weight,” she says. “But, if you’re short of breath, it may not mean you’re out of shape. Know the signs and symptoms—you are your own best advocate.”

 

Get to Know Your Meds (and Your Family History)

Using estrogen-based birth control (pills, patches, and rings) comes with a risk of blood clots, though it’s relatively small. “The overwhelming majority of women on birth control pills do not have problems,” says Ansell.

But, it’s important to note that smoking, being obese, or having a family history of clotting disorders while you’re taking estrogen can all increase the risk.

Check your family tree for clotting disorders before your next appointment for hormonal birth control—and communicate the findings with your doctor. The most common inherited disorder leading to blood clots is Factor V Leiden, which is typically suspected in “individuals who develop blood clots at a young age, who are white with European ancestry, have a family history of clots, or have blood clots in unusual sites,” says Ansell.

If you’re already on estrogen-based birth control, burn the list of DVT and PE symptoms into your brain. And if you feel strongly that something is amiss—trust your instincts and see your doctor.

 

Wiggle Your Way Across the Ocean

Those warnings you see in the back of airline magazines? They do warrant a few seconds of your attention. “Individuals who undertake long distance air travel (greater than five hours) and are relatively immobile have a slightly greater chance of developing a clot,” says Ansell. And, the possibility of travel-related DVT is amplified somewhat with pre-existing factors (like taking estrogen-containing birth control, pregnancy, or obesity)—however, it’s important to note that the overall risk of clotting with air travel still remains small.

Even so, if you’re traveling internationally or cross-country, it’s imperative to get out of your seat every hour and move. “Get in the habit of fidgeting when you’re sitting,” says Ansell. Point your toes downward and upward, make circles, and heck, even try spelling out the alphabet. The key is to keep the blood flowing.

And, although being well-hydrated (a.k.a. asking the kind flight attendant for ice water instead of extra ice for your vodka cranberry) is never a bad idea—there is no definitive evidence to show that dehydration increases DVT risk. Pushing fluids might, however, push you to get up more frequently to use the facilities, and reduce your risk that way.

 

While you don’t need to be overwhelmingly alarmed about your blood clot risk, you should definitely be aware. “The bad news is that we’re talking about 100,000 deaths per year from blood clots,” says Alan P. Brownstein, MPH, CEO of The National Blood Clot Alliance. “But the good news is that most of them can be prevented.”

 

Photo courtesy of sakhorn38.

About the Author

Varci Vartanian is a jack (er, Jill) of all trades. After a successful career in healthcare, she traded her lab coat for her current position as chief temper tantrum tamer/play date consultant for her two-year-old. She also enjoys writing short stories, freelance magazine work, and carbohydrates. Follow her on Twitter @varci_vartanian.

12 comments
Lajuden
Lajuden

I read this article because I have had, for the past few days, pretty severe pain in the front of my knee and the back of my leg (right side). I figured I had just pulled something, as it hurts to put pressure on it when walking. Last night I woke up in the middle of the night with some pretty severe pain in my leg, although it kind of does feel like muscle strain. This morning, it is still there, but also feeling some pain in the upper part of my leg... there is no redness, swelling, or anything like that. I do not have insurance, and hate to go to ER, but would like to know what you all think. Thanks!

Elliott B
Elliott B moderator

@Lajuden Since we aren't doctors we really can't say.  If you really are concerned it's always best to check with a doctor.  You could also check for low-cost clinics in your area, that are usually fairly cheap and don't require insurance.  

Online Gym
Online Gym

Gees, that's a hell of a run with problems. You are so lucky to be alive I'm glad to here you are ok. Giovanna I'm sorry for your loss.

Emma
Emma

Compression stockings work great to prevent blood pooling in lower legs and clotting during long flights too! Sigvaris is the brand I use :)

Varci
Varci

Hi Genevieve- Thank you for the information concerning the possible increased risk of blood clots using drospirenone-containing birth control (Beyaz, Safyral, Yasmin and Yaz). We were aware of the investigation-- but the FDA had not published its completed review of recent studies on the risk of blood clots in women taking drospirenone-containing birth control pills at the time of our publication.

On April 10, 2012, the FDA updated drug labels for drospirenone-containing birth control pills. The new labels will report that some epidemiologic studies showed as high as a three-fold increase in the risk of blood clots whereas other epidemiological studies found no additional risk of blood clots. At this time, the FDA has concluded that the risk for clots may be higher for drospirenone-containing products.

Per the FDA's Drug Safety Communication published on April 10, 2012, http://www.fda.gov/Drugs/DrugSafety/ucm299305.htm :"Women should talk to their healthcare professional about their risk for blood clots before deciding which birth control method to use. Healthcare professionals should consider the risks and benefits of drospirenone-containing birth control pills and a woman’s risk for developing a blood clot before prescribing these drugs."

In addition, women taking drospirenone-containing birth control pills should know the signs/symptoms of DVT/PE. (Although it’s important to note the overall risk of developing a clot still remains low while using a hormonal birth control method).

Lastly, the decision to take an anticoagulant (like aspirin) to reduce clot risk should be done under the supervision of a licensed healthcare professional. Anticoagulation therapy should be prescribed on a case–by-case basis after review of a patient's medical history and discussion of risk versus benefit.

Genevieve
Genevieve

I'm surprised you didn't mention the information regarding the recent Yaz, Yasmin, etc. FDA ruling. The risk for PE from birth control pills is generally low (taking into account family history), but certain pills that contain drospirenone account for most of the BC related PE events, with a risk 2-3 times higher than other BC pills. If you want to educate women, you should tell them to check their pills for that synthetic progestin. Additionally, most PE risks from BC and even from flying are mitigated by taking aspirin. In fact, most women over a certain age should consider taking baby aspirin every day for cardiovascular health, and general inflammation mitigation.

Giovanna
Giovanna

Thanks for sharing your story, Kate. My mother passed away after experiencing only the first symptoms described here (pulled calf muscle feeling), which we didn't know was a blood clot.

The next morning, she said she wasn't feeling well, and then was unresponsive. The blood clot had traveled quickly and was apparently got stuck in her lungs. The doctors said that it moved so quickly there wasn't anything that they could have done.

It's not often that you get as many warning signs as Kate did. If you think it could be a blood clot, see your doctor and ask for a test.

On a positive note, I've tested negative for a predisposition to blood clots.

Thanks, Daily Muse and Kate, for bringing awareness to this often overlooked problem!

Anna Miller
Anna Miller

The timing of this piece hits close to home. A friend's mother just passed away after a blood clot following surgery; another friend's wife is currently hospitalized for a stroke-- she's only in her 20's. No one is immune from blood clots, be they DVT-related or otherwise, and getting help just minutes sooner makes a difference. Thank you for helping to spread the word.

Varci
Varci

Alex- I so appreciate Kate sharing with our readers. Her story could save a life.

Alex
Alex

Varci; Thanks for getting the word out about the risk factors and symptoms of such an under-reported affliction.

-Kate's husband

Varci
Varci

Hi Erin! Your overall risk of developing a clot with air travel is small, but it's still important to educate yourself on the risk factors, warning signs and how to prevent a DVT/PE.

Blood clots are treated with a variety of blood-thinning medications. For more detailed information on all things clot-related-- check out The National Blood Clot Alliance's website at http://www.stoptheclot.org/

Erin
Erin

Wow, I travel all the time (and take birth control) and I had no idea this was a threat. Do you know how this is treated once it's discovered?